This post is to share a quick update on SCCM 2006 Rollup Update Known Issue | Hold Off | ConfigMgr. We have released a post about HFRU ConfigMgr 2006 Hotfix KB4578605 SCCM | Update Rollup | 22 Fixes. Microsoft shared a known issue with that patch if you are using Co-Management features like enrollment/re-enrollment.
Rollup Update Known Issue
David James mentioned in the latest Tweet to hold off this HFRU deployment. Microsoft is planning to release a fix to this issue by end of this week.